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| 1 | Pioglitazone 15mg
Generic name: Actos Size: 30
| $31.33 |  |
| | 2 | Pioglitazone 30mg
Generic name: Actos Size: 30
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| | 3 | Pioglitazone 15mg
Generic name: Actos Size: 60
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| | 4 | Pioglitazone 30mg
Generic name: Actos Size: 60
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| | 5 | Pioglitazone 15mg
Generic name: Actos Size: 90
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| | 6 | Pioglitazone 30mg
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| | 7 | Actos
Generic name: Pioglitazone Size: 30 mg
| 15% discount | |
| | 8 | Pioglitazone
Generic name: Actos (Zactos), Pioglitazone Size: 30 mg
| 15% discount | |
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Actos prescription: Pioglitazone is used for the treatment of type II diabetes along with a healthy diabetic diet, regular exercise, weight control, smoking reduction, and careful monitoring of blood glucose. Pioglitazone may be used alone or in combination with metformin, a drug in a different class of anti-diabetic drugs, that also lowers blood glucose. Since it requires naturally-secreted insulin to be effective, pioglitazone is not recommended in type I diabetes where the amount of insulin is very low or absent. Nevertheless, pioglitazone is approved for treating type II diabetes in combination with insulin as well as another class of anti-diabetic drugs, the sulfonylureas. Pioglitazone is a drug that reduces the amount of glucose (sugar) in the blood. It is in a class of anti-diabetic drugs called 'thiazolidinediones' that are used in the treatment of type II diabetes. The other member in this class is rosiglitazone (Avandia). (Another member of this class, troglitazone or Rezulin, was removed from the market because of liver toxicity.) Patients with type II diabetes cannot make enough insulin, and the cells of their body do not respond normally to the reduced amounts of insulin that are present. (Insulin is the hormone produced by the pancreas that stimulates cells to remove glucose from the blood.) Pioglitazone often is referred to as an 'insulin sensitizer' because it attaches to the insulin receptors on cells throughout the body and causes the cells to become more sensitive (more responsive) to insulin. As a result, more glucose is removed from the blood. At least some insulin must be produced by the pancreas in order for pioglitazone to work.
Actos use: Pioglitazone is an antihyperglycemic agent. It helps the body respond better to insulin and it reduces the amount of sugar produced by the liver. It can help control blood sugar levels. Pioglitazone is used, along with diet and exercise, in the treatment of non-insulin-dependent diabetes mellitus (type II diabetes). Pioglitazone may also be used with a sulfonylurea (e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage).
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Why is this drug prescribed?
Actos tablets contain the active ingredient pioglitazone hydrochloride, which is a type of drug called a thiazolidinedione or glitazone. It is used to help control blood sugar levels in people with type 2 diabetes.
People with diabetes have a deficiency or absence of a hormone produced by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar in the blood. In type 2 diabetes the pancreas does not produce sufficient insulin and the cells of the body are resistant to the low levels of insulin circulating in the blood. Insulin would normally make the cells remove sugar from the blood, hence in type 2 diabetes blood sugar levels can rise too high.
Pioglitazone helps to lower blood glucose levels by increasing the sensitivity of liver, fat and muscle cells, to insulin. This enables the cells to remove glucose from the blood more effectively. Pioglitazone also reduces the amount of glucose produced by the liver, and preserves the functioning of the cells in the pancreas that produce insulin. The overall effect of this drug is therefore to help the body control blood sugar levels and prevent them becoming too high.
Treatments
* Type 2 diabetes.
Pioglitazone can be used on its own to treat people with type 2 diabetes, particularly overweight people, whose blood sugar is not sufficiently controlled by diet and exercise alone, and who cannot take metformin. Metformin is the standard first-line drug for overweight people with type 2 diabetes inadequately controlled by diet.
Pioglitazone can also be used in combination with metformin or another type of antidiabetic drug known as a sulphonylurea, eg gliclazide, or both, for people with type 2 diabetes whose blood sugar is not controlled by the maximum doses of these drugs.
It can also be used in combination with insulin for type 2 diabetics whose blood sugar is not sufficiently controlled by insulin and who cannot take metformin.
What side effects can this drug cause?
* Visual disturbances
* Weight gain
* Decreased sense of touch
* Upper airway infections
* Low red blood cell count
* Pain in the joints
* Headache
* Excessive fluid retention in the body tissues, resulting in swelling
* Blood in the urine
* Impotence
* Dizziness
* Excess gas in the stomach and intestines
* Difficulty in sleeping
* Low blood glucose level, particularly if taken in combination with a sulphonylurea drug, eg gliclazide, or insulin
* Presence of glucose in the urine
* Presence of protein in the urine
* Sweating |
