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Celebrex used: The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any of our products. Celebrex is a non-steroidal anti-inflammatory drug (NSAID) that represents a huge breakthrough in the treatment of pain, inflammation, and stiffness of arthritis. Celebrex (CELECOXIB) is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation
Celebrex prescription: Anti-inflammatory. Celebrex is used to reduce pain and inflammation due to osteoarthritis or rheumatoid arthritis. Anti-inflammatories have been available for 30 years or more, and may sometimes cause stomach irritation and less commonly stomach ulcers. Recently, new anti-inflammatories have been developed that are less irritating to the stomach. These are called COX 2 inhibitors. Celebrex is the first COX 2 inhibitor to be available on prescription.
Celebrex use: Celebrex is used to: relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis in adults. Reduce the number of colorectal polyps in patients with Familial Adenomatous Polyposis (FAP). FAP is an inherited disorder in which the rectum and colon are covered with many polyps. Celebrex should be used along with the usual care for FAP patients such as surgery and monitoring of the lower gastrointestinal tract.
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Why is this drug prescribed?
Celebrex capsules contain the active ingredient celecoxib, which is a type of drug known as a non-steroidal anti-inflammatory drug.
NSAIDs work by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in producing prostaglandins, in response to injury or certain diseases. These prostaglandins cause pain, swelling and inflammation. Because NSAIDs block the production of these prostaglandins, they are effective at relieving pain and inflammation.
Cyclo-oxygenase does not only produce prostaglandins that cause inflammation. It also produces prostaglandins that have useful roles in the body. There are two different forms of cyclo-oxygenase, COX-1 and COX-2. COX-2 is the form that produces prostaglandins that cause inflammation. COX-1 does not produce inflammatory prostaglandins, but does produce others that have useful effects, including some that are involved in maintaining a healthy stomach and intestinal lining.
Traditional NSAIDs, such as ibuprofen or diclofenac, block the action of both COX-1 and COX-2, and this is why they can sometimes cause side effects such as stomach irritation and peptic ulcers. Celecoxib belongs to a new generation of NSAIDs that selectively block the action of COX-2. This means that it stops the production of inflammatory prostaglandins, without stopping the production of prostaglandins that protect the stomach and intestines. It therefore reduces pain and inflammation, but is less likely than traditional NSAIDs to cause side effects on the stomach and intestines.
Treatments
* Rheumatoid arthritis
* Osteoarthritis
What side effects can this drug cause?
* Difficulty in sleeping
* Inflammation of the sinuses
* Dizziness
* Inflammation of the throat
* Inflammation of the lining of the nose causing a blocked or runny nose
* Disturbances of the gut such as indigestion, diarrhoea, constipation, nausea, vomiting, flatulence or abdominal pain
* Retention of water in the body tissues swelling, particularly of the legs and ankles
* Skin reactions such as rash
* Blurred vision
* Tiredness
* Anxiety
* Depression
* Increased potassium level in the blood
* Pins and needles
* Sensation of ringing or other noise in the ears
* Shortness of breath
* High blood pressure
* Heart attack or stroke
* Ulceration or bleeding of the stomach or intestines
* Liver, kidney or blood disorders
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