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Polycillin-N prescription: Ampicillin is one of the most widely prescribed antibiotics. It is considered a penicillin and is a close relative of another penicillin, amoxicillin. Unlike penicillin, ampicillin and amoxicillin can penetrate and prevent the growth of certain types of bacteria, called gram-negative bacteria. Ampicillin is used mainly to treat infections of the middle ear, sinuses, bladder, kidney, and uncomplicated gonorrhea. It also is used intravenously to treat meningitis and other serious infections. Oral ampicillin (or amoxicillin) is effective against susceptible bacteria causing infections of the middle ear, sinuses, bladder, and kidney. Only mild to moderate infections are treated with oral ampicillin. Bacteria against which ampicillin often is effective include: enterococci, Listeria monocytogenes, Neisseria gonorrhoeae, Neisseria meningitidis, some Hemophilus influenzae, Gardnerella vaginalis, Bordetella pertussis, and some E. coli, Proteus mirabilis, Salmonella, and Shigella. Susceptibilities of bacteria to antibiotics vary from location to location. Thus, some doctors may use ampicillin or amoxicillin first for some infections, whereas other doctors may use more 'broad-spectrum' antibiotics.
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